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Analyses from a phase II basket trial highlighted the potential role of T-DM1 in HER2 -mutant NSCLC patients, administered at the dose of 3.6 mg/kg intravenously every 3 weeks (Q3W)

The metabolic activity of tumor can also affect the changes of TME, and immune escape can be achieved by inhibiting the function of T cells (205, 206)

[DOI] [PMC free article] [PubMed] [Google Scholar] Pineda J.A., Aono M., Sheng H., Lynch J., Wellons J.C., Laskowitz D.T., Pearlstein R.D., Bowler R., Crapo J., Warner D.S

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